“When you go from DNA all the way to protein, we know there is a loss of information… All your drugs are actually acting against
“Pharmacogenomics is germline genetic testing that helps us understand when our genes would dictate that for a growing list of medications, whether we need a
Meeting Summary “Biology is about systems and processes… but the process of interacting with a patient, with a physician, is actually more complex (than the
Meeting Summary “I don’t think we know how to build these (mechanistic simulation) models (that would predict drug response or resistance for individual patients). There’s
Meeting Summary “Genes don’t reliably predict response to treatment, and the gene mutations or expression in cells don’t reliably predict the expression of proteins in
Meeting Summary “We get the fresh sample, we process it, we use what we need for drug testing, and we freeze them down. If we
Meeting Summary “We’ve had DNA and RNA seq. Those are all great proxies for proteins. I don’t want to monkey around anymore. I want to
Meeting Summary How can physicians be convinced to overcome concerns of safety, reimbursement, and liability to prescribe novel regimens (personalized drug combinations, dosing, and sequences),
Meeting Summary Advanced cancer patient Brian McCloskey shared the 17 treatment options that have been identified for him by various sources, including Cancer Commons/xCures, CureMatch, and Massive
Meeting Summary “The way that you’ve built your whole value chain is one of the more complete solutions that I’ve seen.” – Brian McCloskey Selin
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